T_Dia
05-07-2009, 02:12 PM
Researchers pooled data from nearly 6,900 patient records from the Scientific Registry of Transplant Recipients database. All patients had been on a waiting-list for a transplant between 1997 and 2005. Patient and kidney graft survival were compared with 84-month post-transplant survival.
Transplant recipients were categorized as:
* Recipients of simultaneous pancreas-kidney transplant with functioning pancreas graft at 12 months post-transplant.
* Recipients of living-donor kidney alone transplant.
Patients with a successful simultaneous pancreas-kidney transplant with a functioning pancreas and kidney at one year had an 88.6% survival rate vs. an 80% survival rate for those treated with a living-donor kidney alone transplant, a 73.9% survival rate for recipients of simultaneous pancreas-kidney transplant with loss of pancreas graft function, and a 64.8% rate for those who received a deceased-donor kidney alone transplant (P<.001).
In addition, unadjusted graft survival rate was highest among the simultaneous pancreas-kidney transplant group (P=.015).
Researchers also reported that patients who received simultaneous pancreas-kidney transplantation were about 2% more likely to die during the first year after transplantation. There was also a 10% to 15% chance that the transplanted pancreas would fail during the first year, decreasing the long-term survival rate to 74%.
Full Article (http://www.endocrinetoday.com/view.aspx?rid=39518).
Transplant recipients were categorized as:
* Recipients of simultaneous pancreas-kidney transplant with functioning pancreas graft at 12 months post-transplant.
* Recipients of living-donor kidney alone transplant.
Patients with a successful simultaneous pancreas-kidney transplant with a functioning pancreas and kidney at one year had an 88.6% survival rate vs. an 80% survival rate for those treated with a living-donor kidney alone transplant, a 73.9% survival rate for recipients of simultaneous pancreas-kidney transplant with loss of pancreas graft function, and a 64.8% rate for those who received a deceased-donor kidney alone transplant (P<.001).
In addition, unadjusted graft survival rate was highest among the simultaneous pancreas-kidney transplant group (P=.015).
Researchers also reported that patients who received simultaneous pancreas-kidney transplantation were about 2% more likely to die during the first year after transplantation. There was also a 10% to 15% chance that the transplanted pancreas would fail during the first year, decreasing the long-term survival rate to 74%.
Full Article (http://www.endocrinetoday.com/view.aspx?rid=39518).